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Clinical laboratory testing and in vitro diagnostic test systems. Reference method for testing the in vitro activity of antimicrobial agents against yeast of fungi involved in infectious diseases Ingestion-build-47182 as well as the disturbance1 Scope This International Standard describes a method for testing the susceptibility to antifungal agents of yeasts, including Candida spp. and Cryptococcus neoformans, that cause infections. The reference method described here has not been used in studies of the yeast forms of dimorphic fungi, such as B. dermatitidis and or H. capsulatum variety capsulatum. Moreover, testing filamentous fungi (moulds) introduces several additional problems in